Type of Preparation:
Direct Smear
Magnification:
high power
Interpretation:
Fig. 5.2b Neoplasm: SUMP
Cytomorphologic Criteria:
Cellular aspirate; neoplastic cells: oncocytic or oncocytoid features that cannot be classified further. The usual criteria for a pleomorphic adenoma are as follows:
• Distinctive chondromyxoid matrix: Best appreciated using Romanowsky stains
(Diff-Quik®, Giemsa), as a bright magenta matrix with a distinct fibrillary/feathery
quality; grey to translucent green in Papanicolaou-stained preparations
• Myoepithelial cells: Variety of shapes (polygonal, plasmacytoid, round, spindle,
and clear), bland nuclear features, often the predominant cell type (Fig. 5.2)
• Ductal epithelial cells: Bland nuclear features, small groups recapitulating ductal
structures
• Iconic PA:Modestly cellular with readily identifiable, abundant fibrillar matrix,
bland ductal epithelial and myoepithelial cells
Explanatory Notes:
FNA of cellular oncocytic/oncocytoid or plasmacytoid neoplasm showing loose groups and dispersed neoplastic cells with bland oncocytic/plasmacytic features. This actually was an FNA of a pleomorphic adenoma with highly cellular matrix-poor tumor with a predominance of oncocytoid/plasmacytoid appearing cells,