Type of Preparation:
Direct Smear
Magnification:
High Power Magnification
Interpretation:
Fig. 4.1b Atypia of Undetermined Significance (AUS)
Cytomorphologic Criteria:
Squamous, oncocytic, or other metaplastic changes indefinite for a neoplasm.
In addition, the FNA exhibits an atypical cytomorphologic feature that excludes the possibility of classifying it as “Non-Diagnostic.” Most samples will represent reactive atypia or poorly sampled neoplasms.
Explanatory Notes:
Salivary gland FNAs with suboptimal cellularity or with artifacts can raise uncertainty as to whether the aspirated lesion is neoplastic or not. Sparsely cellular aspirates composed of basaloid cells can raise a differential diagnosis that includes chronic sialadenitis and a basaloid neoplasmIn addition, the FNA exhibits an atypical cytomorphologic feature that excludes the possibility of classifying it as “Non-Diagnostic.” Most samples will represent reactive atypia or poorly sampled neoplasms.d.